p-Chlorophenylalanine

Cat. No. 0938 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Tryptophan hydroxylase inhibitor

纯度： ≥99% (HPLC)

引用文献 (2)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for p-Chlorophenylalanine

p-Chlorophenylalanine is a binds irreversibly to tryptophan hydroxylase to cause depletion of serotonin in the brain.

技术数据 for p-Chlorophenylalanine

分子量	199.64
公式	C₉H₁₀ClNO₂
储存	Store at RT
纯度	≥99% (HPLC)
CAS Number	7424-00-2
PubChem ID	4652
InChI Key	NIGWMJHCCYYCSF-UHFFFAOYSA-N
Smiles	NC(C(O)=O)CC1=CC=C(Cl)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for p-Chlorophenylalanine

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	1eq. NaOH		10

制备储备液 for p-Chlorophenylalanine

以下数据基于产品分子量 199.64。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.1 mM	50.09 mL	250.45 mL	500.9 mL
0.5 mM	10.02 mL	50.09 mL	100.18 mL
1 mM	5.01 mL	25.05 mL	50.09 mL
5 mM	1 mL	5.01 mL	10.02 mL

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产品说明书 for p-Chlorophenylalanine

分析证书/产品说明书

化学品安全技术说明书

参考文献 for p-Chlorophenylalanine

参考文献是支持产品生物活性的出版物。

Datla and Curzon (1996) Effect of p-chlorophenylalanine at moderate dosage on 5-HT and 5-HIAA concentrations in brain regions of control and p-chloroamphetamine treated rats. Neuropharmacology 35 315 PMID: 8783206

Koyuncuoglu et al (1975) The effects of DL-p-chlorophenylalanine and DL-α-methyl-p-tyrosine on the brain catecholamine, serotonin and free amino acid contents in rat. Psychopharmacologia 45 163 PMID: 129787

If you know of a relevant reference for p-Chlorophenylalanine, please let us know.

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关键词: p-Chlorophenylalanine, p-Chlorophenylalanine supplier, Tryptophan, hydroxylases, inhibitors, inhibits, serotonin, depletion, PCPA, fenclonine, 5-HT-Related, Hydroxylases, 5-HT3, Receptors, 0938, Tocris Bioscience

2 篇 p-Chlorophenylalanine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 p-Chlorophenylalanine 的部分引用包括：

Tullius et al (2014) NAD+ protects against EAE by regulating CD4+ T-cell differentiation. Nat Commun 5 5101 PMID: 25290058

Hernandez et al (2012) Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals. Proc Natl Acad Sci U S A 302 E1009 PMID: 22318950

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