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Submit ReviewPF 750
说明： Selective FAAH inhibitor
化学名： N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide
纯度： ≥98% (HPLC)
生物活性 for PF 750
PF 750 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active.
技术数据 for PF 750
| 分子量 | 345.44 |
| 公式 | C22H23N3O |
| 储存 | Store at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 959151-50-9 |
| PubChem ID | 25154868 |
| InChI Key | BIODYGOZWZNCAG-UHFFFAOYSA-N |
| Smiles | O=C(NC4=CC=CC=C4)N(CC3)CCC3CC2=CC1=CC=CC=C1N=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for PF 750
参考文献 for PF 750
参考文献是支持产品生物活性的出版物。
Ahn et al (2007) Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 46 13019 PMID: 17949010
Mileni et al (2008) Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc.Natl.Acad.Sci.USA 105 12820
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关键词: PF 750, PF 750 supplier, Selective, FAAH, inhibitors, inhibits, Anandamide, Amidase, Fatty, Acid, Amide, Hydrolases, PF750, Hydrolase, (FAAH), Other, Cannabinoids, 3307, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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