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Submit ReviewPhalloidin is a promotes actin polymerization. Decreases dissociation rate constant for actin subunits from filament ends; lowers critical concentration for polymerization.
分子量 | 788.87 |
公式 | C35H48N8O11S |
序列 | ATCXAWL (Modifications: Cyclic Cys-3-Trp-6, X=Hyp, D-Thr-2) |
储存 | Store at -20°C |
纯度 | ≥90% (HPLC) |
CAS Number | 17466-45-4 |
PubChem ID | 90488951 |
InChI Key | KPKZJLCSROULON-RCGKFKHASA-N |
Smiles | O=C([C@H](N5)CSC(NC3=C2C=CC=C3)=C2C[C@@H](C(N[C@@H](C[C@](O)(C)CO)C(NC(C(N[C@H]([C@H](C)O)C5=O)=O)C)=O)=O)NC([C@@H](N[C@]4=O)C)=O)N1[C@H]4C[C@@H](O)C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性 | Soluble to 1 mg/ml in water |
参考文献是支持产品生物活性的出版物。
Diensthuber et al (2011) Phalloidin perturbs the interaction of human non-muscle myosin isoforms 2A and 2C1 with F-actin. FEBS Lett. 585 767 PMID: 21295570
Cooper (1987) Effects of cytochalasin and phalloidin on actin. J.Cell Biol. 105 1473 PMID: 3312229
Coluccio and Tilney (1984) Phalloidin enhances actin assembly by preventing monomer dissociation. J.Cell Biol. 99 529 PMID: 6746738
Wehland et al (1977) Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth. Proc.Natl.Acad.Sci.USA 74 5613 PMID: 341163
If you know of a relevant reference for Phalloidin, please let us know.
关键词: Phalloidin, Phalloidin supplier, actin, polymerization, polymerisation, promoters, Actin, 4535, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Phalloidin 的部分引用包括:
Zhen et al (2009) Dopamine D4 receptors regulate AMPA receptor trafficking and glutamatergic transmission in GABAergic interneurons of prefrontal cortex. J Neurosci 29 550-62 PMID: 19144855
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