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PluriSln 1

Cat. No. 4847 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： SCD-1 inhibitor
别名： NSC 14613
化学名： 4-Pyridinecarboxylic acid 2-phenylhydrazide
纯度： ≥99% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for PluriSln 1

PluriSln 1 is a stearoyl-CoA desaturase 1 (SCD1) inhibitor. Used to selectively eliminate undifferentiated human pluripotent stem cells (hPSCs) from culture; induces ER stress, attenuates protein synthesis and induces apoptosis in hPSCs. Prevents teratoma formation in immunocompromised mice.

化合物库 for PluriSln 1

PluriSln 1 is also offered as part of the Tocriscreen Stem Cell Library. 了解 Tocris 化合物库的更多信息。

技术数据 for PluriSln 1

分子量 213.24
公式 C12H11N3O
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 91396-88-2
PubChem ID 225362
InChI Key HUDWXDLBWRHCKO-UHFFFAOYSA-N
Smiles O=C(NNC2=CC=CC=C2)C1=CC=NC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for PluriSln 1

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 21.32 100
ethanol 21.32 100

制备储备液 for PluriSln 1

以下数据基于产品分子量 213.24。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.69 mL 23.45 mL 46.9 mL
5 mM 0.94 mL 4.69 mL 9.38 mL
10 mM 0.47 mL 2.34 mL 4.69 mL
50 mM 0.09 mL 0.47 mL 0.94 mL

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参考文献 for PluriSln 1

参考文献是支持产品生物活性的出版物。

Ben-David et al (2013) Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen. Cell Stem Cell 12 167 PMID: 23318055

If you know of a relevant reference for PluriSln 1, please let us know.

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关键词: PluriSln 1, PluriSln 1 supplier, PluriSln1, stearoyl-CoA, desaturase, SCD1, inhibitors, inhibits, human, pluripotent, stem, cells, hPSCs, selective, elimination, eliminates, NSC, 14613, Stearoyl-CoA, 9-desaturase, ESCs, and, iPSC, 4847, Tocris Bioscience

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