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Submit ReviewProcaterol hydrochloride is a specific and very potent β2 agonist.
Procaterol hydrochloride is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。
分子量 | 326.82 |
公式 | C16H22N2O3.HCl |
储存 | Store at RT |
纯度 | ≥99% (HPLC) |
CAS Number | 62929-91-3 |
PubChem ID | 43091 |
InChI Key | AEQDBKHAAWUCMT-CVHDTDHSSA-N |
Smiles | O=C1C=CC2=C(C(O)=CC=C2[C@@]([H])(O)[C@@](NC(C)C)(CC)[H])N1.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 32.68 | 100 | |
DMSO | 32.68 | 100 |
以下数据基于产品分子量 326.82。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 3.06 mL | 15.3 mL | 30.6 mL |
5 mM | 0.61 mL | 3.06 mL | 6.12 mL |
10 mM | 0.31 mL | 1.53 mL | 3.06 mL |
50 mM | 0.06 mL | 0.31 mL | 0.61 mL |
参考文献是支持产品生物活性的出版物。
Kotsonis and Majewski (1994) Facilitation by procaterol, a β-adrenoceptor agonist, of noradrenaline release in the pithed rat independently of angiotensin II formation. Br.J.Pharmacol. 113 781 PMID: 7858867
Lakhlani et al (1994) Pharmacological characterization and anatomical localization of prejunctional β-adrenoceptors in the rat kidney. Br.J.Pharmacol. 111 1296 PMID: 8032617
Yoshizaki et al (1976) Sympathomimetic amines having a carbostyril nucleus. J.Med.Chem. 19 1138 PMID: 10441
Yoshizaki et al (1977) Isomers of erythro-5-(1-hydroxy-2-isoproylaminobutyl)-8-hydroxycarbostyril, a new bronchodilator. J.Med.Chem. 20 1103 PMID: 894683
If you know of a relevant reference for Procaterol hydrochloride, please let us know.
关键词: Procaterol hydrochloride, Procaterol hydrochloride supplier, Potent, α2-adrenoceptor, beta2-adrenoceptor, b2-adrenoceptor, β2-adrenergic, α2-adrenergic, beta2-adrenergic, b2-adrenergic, agonist, receptors, Adrenergic, Beta-2, Receptors, 1102, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Procaterol hydrochloride 的部分引用包括:
Schutsky et al (2011) Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling. J Neurosci 31 14172 PMID: 21976502
Sivamani et al (2009) Stress-mediated increases in systemic and local epinephrine impair skin wound healing: potential new indication for β blockers. J Pharmacol Exp Ther 6 e12 PMID: 19143471
Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Front Cell Neurosci 329 350 PMID: 19144685
Copik et al (2015) Isoproterenol acts as a biased agonist of the α-1A-adrenoceptor that selectively activates the MAPK/ERK pathway. PLoS Med 10 e0115701 PMID: 25606852
Rieg et al (2012) Cardiovascular agents affect the tone of pulmonary arteries and veins in precision-cut lung slices. PLoS One 6 e29698 PMID: 22216346
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.