Procaterol hydrochloride

Pricing Availability   Qty
说明: Potent β2 agonist
化学名: (±)-erythro-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]carbostyril hydrochloride
纯度: ≥99% (HPLC)
说明书
引用文献 (5)
评论
文献 (1)

生物活性 for Procaterol hydrochloride

Procaterol hydrochloride is a specific and very potent β2 agonist.

化合物库 for Procaterol hydrochloride

Procaterol hydrochloride is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for Procaterol hydrochloride

分子量 326.82
公式 C16H22N2O3.HCl
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 62929-91-3
PubChem ID 43091
InChI Key AEQDBKHAAWUCMT-CVHDTDHSSA-N
Smiles O=C1C=CC2=C(C(O)=CC=C2[C@@]([H])(O)[C@@](NC(C)C)(CC)[H])N1.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Procaterol hydrochloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 32.68 100
DMSO 32.68 100

制备储备液 for Procaterol hydrochloride

以下数据基于产品分子量 326.82。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.06 mL 15.3 mL 30.6 mL
5 mM 0.61 mL 3.06 mL 6.12 mL
10 mM 0.31 mL 1.53 mL 3.06 mL
50 mM 0.06 mL 0.31 mL 0.61 mL

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产品说明书 for Procaterol hydrochloride

分析证书/产品说明书
选择另一批次:

参考文献 for Procaterol hydrochloride

参考文献是支持产品生物活性的出版物。

Kotsonis and Majewski (1994) Facilitation by procaterol, a β-adrenoceptor agonist, of noradrenaline release in the pithed rat independently of angiotensin II formation. Br.J.Pharmacol. 113 781 PMID: 7858867

Lakhlani et al (1994) Pharmacological characterization and anatomical localization of prejunctional β-adrenoceptors in the rat kidney. Br.J.Pharmacol. 111 1296 PMID: 8032617

Yoshizaki et al (1976) Sympathomimetic amines having a carbostyril nucleus. J.Med.Chem. 19 1138 PMID: 10441

Yoshizaki et al (1977) Isomers of erythro-5-(1-hydroxy-2-isoproylaminobutyl)-8-hydroxycarbostyril, a new bronchodilator. J.Med.Chem. 20 1103 PMID: 894683


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关键词: Procaterol hydrochloride, Procaterol hydrochloride supplier, Potent, α2-adrenoceptor, beta2-adrenoceptor, b2-adrenoceptor, β2-adrenergic, α2-adrenergic, beta2-adrenergic, b2-adrenergic, agonist, receptors, Adrenergic, Beta-2, Receptors, 1102, Tocris Bioscience

5 篇 Procaterol hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Procaterol hydrochloride 的部分引用包括:

Schutsky et al (2011) Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling. J Neurosci 31 14172 PMID: 21976502

Sivamani et al (2009) Stress-mediated increases in systemic and local epinephrine impair skin wound healing: potential new indication for β blockers. J Pharmacol Exp Ther 6 e12 PMID: 19143471

Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Front Cell Neurosci 329 350 PMID: 19144685

Rieg et al (2012) Cardiovascular agents affect the tone of pulmonary arteries and veins in precision-cut lung slices. PLoS One 6 e29698 PMID: 22216346


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Depression Poster

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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.