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Submit ReviewProstaglandin F2α is a prostaglandin E2 and F2α receptor agonist. Naturally-occurring prostaglandin and potent vasoconstrictor. Induces cardiomyocyte hypertrophy in vitro. Exhibits luteolytic activity.
分子量 | 475.62 |
公式 | C20H34O5.C4H11NO3 |
储存 | Store at -20°C |
纯度 | ≥98% (HPLC) |
CAS Number | 38562-01-5 |
PubChem ID | 5282415 |
InChI Key | IYGXEHDCSOYNKY-RZHHZEQLSA-N |
Smiles | O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1.NC(CO)(CO)CO |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
DMSO | 47.56 | 100 | |
ethanol | 47.56 | 100 |
以下数据基于产品分子量 475.62。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 2.1 mL | 10.51 mL | 21.03 mL |
5 mM | 0.42 mL | 2.1 mL | 4.21 mL |
10 mM | 0.21 mL | 1.05 mL | 2.1 mL |
50 mM | 0.04 mL | 0.21 mL | 0.42 mL |
参考文献是支持产品生物活性的出版物。
Samuelsson et al (1978) Prostaglandins and throboxanes. Annu.Rev.Biochem. 47 997 PMID: 209733
Girsh and Dekel (2002) Involvement of endothelin-1 and its receptors in PGF2α-induced luteolysis in the rat. Mol.Reprod.Dev. 63 71 PMID: 12211063
Lai et al (1996) Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo. Am.J.Physiol. 271 2197
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关键词: Prostaglandin F2alpha, Prostaglandin F2alpha supplier, Dinoprost, tromethamine, salt, prostaglandin, E2, F2a, F2alpha, recepor, agonist, PGF2a, agonists, vasoconstrictor, Prostanoid, Receptors, 4214, Tocris Bioscience
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