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Submit ReviewPSN 375963 hydrochloride
说明： GPR119 receptor agonist
化学名： 4-[5-(4-Butylcyclohexyl)-1,2,4-oxadiazol-3-yl]-pyridine hydrochloride
纯度： ≥98% (HPLC)
生物活性 for PSN 375963 hydrochloride
GPR119 receptor agonist (EC50 values are 8.4 and 7.9 μM at human and mouse receptors respectively). Displays similar potency to the endogenous ligand oleylethanolamide (OEA) (Cat. No. 1484).
技术数据 for PSN 375963 hydrochloride
| 分子量 | 321.84 |
| 公式 | C17H23N3O.HCl |
| 储存 | Desiccate at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 1781834-82-9 |
| PubChem ID | 56972228 |
| InChI Key | ONDLSENXTCSHGC-UHFFFAOYSA-N |
| Smiles | CCCCC(CC3)CCC3C1=NC(C2=CC=NC=C2)=NO1.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for PSN 375963 hydrochloride
参考文献 for PSN 375963 hydrochloride
参考文献是支持产品生物活性的出版物。
Overton et al (2006) Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab. 3 167 PMID: 16517404
Ning et al (2008) Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on Ins secretion in MIN6c4 Insoma cells. Br.J.Pharmacol. 155 1056 PMID: 18724386
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关键词: PSN 375963 hydrochloride, PSN 375963 hydrochloride supplier, GPR119, receptors, agonists, PSN375963, hydrochloride, 3353, Tocris Bioscience
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