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Quinelorane hydrochloride

Cat. No. 1519 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： D2 and D3 agonist
别名： LY 163502
化学名： (5aR,9aR)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
文献 (2)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Quinelorane hydrochloride

Quinelorane hydrochloride is a dopamine D2 and D3 receptor agonist; Ki values are 5.7 and 3.4 nM respectively.

许可信息

Sold with the permission of Eli Lilly and Company

技术数据 for Quinelorane hydrochloride

分子量 319.27
公式 C14H22N4.2HCl
储存 Desiccate at RT
纯度 ≥99% (HPLC)
CAS Number 97548-97-5
PubChem ID 68728
InChI Key WDEMLQIGYYLRRX-OWVUFADGSA-N
Smiles [H][C@]23[C@@](CCCN3CCC)([H])CC1=NC(N)=NC=C1C2.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Quinelorane hydrochloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 7.98 25

制备储备液 for Quinelorane hydrochloride

以下数据基于产品分子量 319.27。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.25 mM 12.53 mL 62.64 mL 125.29 mL
1.25 mM 2.51 mL 12.53 mL 25.06 mL
2.5 mM 1.25 mL 6.26 mL 12.53 mL
12.5 mM 0.25 mL 1.25 mL 2.51 mL

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产品说明书 for Quinelorane hydrochloride

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Quinelorane hydrochloride

参考文献是支持产品生物活性的出版物。

Foreman et al (1989) Preclinical studies on quinelorane, a potent and highly selective D2-DArgic agonist. J.Pharmacol.Exp.Ther. 250 227 PMID: 2526214

Eaton et al (1994) Effects of the selective DArgic D2 agonist quinelorane on the activity of DArgic and noradrenergic neurons projecting to the diencephalon of the rat. J.Pharmacol.Exp.Ther. 268 645 PMID: 7906734

Flietstra and Levant (1998) Comparison of D2 and D3 DA receptor affinity of DArgic compounds in the rat brain. Life Sci. 62 1825 PMID: 9600324

If you know of a relevant reference for Quinelorane hydrochloride, please let us know.

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关键词: Quinelorane hydrochloride, Quinelorane hydrochloride supplier, D2, D3, agonists, Dopamine, D2-like, Non-Selective, Receptors, dopaminergic, LY163502, LY, 163502, Non-selective, 1519, Tocris Bioscience

1 篇 Quinelorane hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Quinelorane hydrochloride 的部分引用包括：

Baca et al (2013) Gene-environment interactions affect long-term depression (LTD) through changes in DA receptor affinity in Snap25 deficient mice. Brain Res 1532 85 PMID: 23939223

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*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

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