主页 / 药理学 / Ion Channels / Ligand-gated Ion Channels / 5-HT3 Receptors / 5-HT3 Receptor Agonists / Quipazine dimaleate

Quipazine dimaleate

Cat. No. 0629 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： 5-HT3 agonist
化学名： 2-(1-Piperazinyl)quinoline dimaleate
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for Quipazine dimaleate

Quipazine dimaleate is a selective 5-HT3 receptor agonist. Also displays antagonist activity at peripheral 5-HT3 receptors. [3H]-Quipazine labels 5-HT3 sites in the cortical membranes.

技术数据 for Quipazine dimaleate

分子量 445.43
公式 C13H15N3.2C4H4O4
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 150323-78-7
PubChem ID 6420043
InChI Key VAOSOCRJSSWBEQ-SPIKMXEPSA-N
Smiles OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C1CN(CCN1)C1=NC2=C(C=CC=C2)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Quipazine dimaleate

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 44.54 100

制备储备液 for Quipazine dimaleate

以下数据基于产品分子量 445.43。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.25 mL 11.23 mL 22.45 mL
5 mM 0.45 mL 2.25 mL 4.49 mL
10 mM 0.22 mL 1.12 mL 2.25 mL
50 mM 0.04 mL 0.22 mL 0.45 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

产品说明书 for Quipazine dimaleate

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for Quipazine dimaleate

参考文献是支持产品生物活性的出版物。

Ireland and Tyers (1987) Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br.J.Pharmacol. 90 229 PMID: 3814920

Peroutka and Hamik (1988) [3H]Quipazine labels 5-HT3 recognition sites in rat cortical membranes. Eur.J.Pharmacol. 148 297 PMID: 3378579

Sharif et al (1991) Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding. Br.J.Pharmacol. 102 919 PMID: 1830236

If you know of a relevant reference for Quipazine dimaleate, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 5-HT3 Receptor Agonists

关键词: Quipazine dimaleate, Quipazine dimaleate supplier, 5-HT3, agonists, Serotonin, Receptors, 0629, Tocris Bioscience

1 篇 Quipazine dimaleate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Quipazine dimaleate 的部分引用包括：

Hutchinson et al (2012) Differential regulation of MeCP2 phosphorylation in the CNS by DA and serotonin. Br J Pharmacol 37 321 PMID: 21956448

您是否知道使用了 Tocris Quipazine dimaleate 的优秀论文？ 请告知我们.

Quipazine dimaleate 的评论

目前没有该产品的评论。 Be the first to review Quipazine dimaleate and earn rewards!

Have you used Quipazine dimaleate?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

5-HT Receptors Scientific Review

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.