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Submit Review(R)-(-)-Deprenyl hydrochloride is a selective inhibitor of monoamine oxidase B (MAO-B).
分子量 | 223.74 |
公式 | C13H17N.HCl |
储存 | Store at RT |
纯度 | ≥99% (HPLC) |
CAS Number | 14611-52-0 |
PubChem ID | 26758 |
InChI Key | IYETZZCWLLUHIJ-UTONKHPSSA-N |
Smiles | C#CCN(C)[C@H](C)CC1=CC=CC=C1.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Gerlach et al (1992) The molecular pharmacology of L-deprenyl. Eur.J.Pharmacol. 226 97 PMID: 1639115
Kaseda et al (1999) Effect of selegeline on DA concentration in the striatum of a primate. Brain Res. 815 44 PMID: 9974121
Kotake et al (1998) Deprenyl decreases an endogenous parkinsonism-inducing compound, 1-benzyl-1,2,3,4-tetrahydroisoquinoline in mice: in vivo and in vitro studies. Brain Res. 787 341 PMID: 9518683
Mercuri et al (1998) Modification of lev. responses by deprenyl (selegiline): an electrophysiological and behavioural study in the rat relevant to Parkinson's disease. Ann.Neurol. 43 613 PMID: 9585355
Merck Index 12 8569
关键词: (R)-(-)-Deprenyl hydrochloride, (R)-(-)-Deprenyl hydrochloride supplier, MAO-B, inhibitors, inhibits, Monoamine, Oxygenases, Oxidases, parkinson's, parkinsons, Selegiline, Oxidase, Adrenergic, Related, Compounds, Dopaminergic-Related, 5-HT-Related, 5-HT3, Receptors, 1095, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.