Ralfinamide mesylate

Name: Ralfinamide mesylate
Brand: Tocris Bioscience
SKU: 4029

Cat. No. 4029 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4029 has been discontinued.

View all Voltage-gated Sodium (Na<sub>V</sub>) Channels products.

说明： Na⁺ channel blocker

化学名： (2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide methanesulfonate

纯度： ≥99% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Ralfinamide mesylate

Ralfinamide mesylate is a sodium channel blocker. Suppresses tetrodotoxin (TTX)-resistant Na⁺ currents approximately twice as selectively as TTX-sensitive currents. Antinociceptive; displays analgesic effects in animal models of inflammatory and neuropathic pain.

技术数据 for Ralfinamide mesylate

分子量	398.45
公式	C₁₇H₁₉FN₂O₂.CH₃SO₃H
储存	Store at +4°C
纯度	≥99% (HPLC)
CAS Number	202825-45-4
PubChem ID	23661379
InChI Key	CHQVNINIGBRKGZ-YDALLXLXSA-N
Smiles	FC(C=CC=C2)=C2COC1=CC=C(CN[C@@H](C)C(N)=O)C=C1.CS(=O)(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Ralfinamide mesylate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Ralfinamide mesylate

参考文献是支持产品生物活性的出版物。

Veneroni et al (2003) Anti-allodynic effect of NW-1029, a novel Na⁺ channel blocker, in experimental animal models of inflammatory and neuropathic pain. Pain 102 17 PMID: 12620593

Yamane et al (2007) Effects of ralfinamide, a Na⁺ channel blocker, on firing properties of nociceptive dorsal root ganglion neurons of adult rats. Exp.Neurol. 208 63 PMID: 17707373

Zhang et al (2008) Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain 139 293 PMID: 18583049

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篇 Ralfinamide mesylate 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 Ralfinamide mesylate 的引用文献。