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Submit ReviewRLLFT-NH2 is a reversed amino acid sequence control peptide for TFLLR-NH2, a PAR1 selective agonist that significantly increases nociceptive threshold.
Active Analog also available.
分子量 | 647.82 |
公式 | C31H53N9O6 |
序列 |
RLLFT (Modifications: Thr-5 = C-terminal amide) |
储存 | Store at -20°C |
CAS Number | 447408-68-6 |
PubChem ID | 56972203 |
InChI Key | ILPOBMZRIPLMBB-GFGQVAFXSA-N |
Smiles | [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Asfaha et al (2002) Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli. Br.J.Pharmacol. 135 1101 PMID: 11877315
Fang et al (2003) Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin. J.Physiol. 549 903 PMID: 12717003
Buresi et al (2004) Activation of proteinase-activated receptor-1 inhibits neurally evoked chloride secretion in the mouse colon in vitro. Am.J.Physiol.Gastrointest.Liver Physiol. 288 G337 PMID: 15345469
关键词: RLLFT-NH2, RLLFT-NH2 supplier, Control, peptide, TFLLR-NH2, PAR, Receptors, Protease-Activated, proteinase-activated, 3393, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 RLLFT-NH2 的部分引用包括:
Chen et al (2012) Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci 32 7622 PMID: 22649241
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