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Submit ReviewRosmarinic acid
说明： GPR35 agonist; anti-inflammatory, cytostatic and antiviral
化学名： [R-(+)]-α-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid
纯度： ≥99% (HPLC)
生物活性 for Rosmarinic acid
Anti-inflammatory, cytostatic and antiviral. Also displays agonist activity at GPR35.
技术数据 for Rosmarinic acid
| 分子量 | 360.32 |
| 公式 | C18H16O8 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 20283-92-5 |
| PubChem ID | 5281792 |
| InChI Key | DOUMFZQKYFQNTF-WUTVXBCWSA-N |
| Smiles | O=C(/C=C/C2=CC(O)=C(O)C=C2)O[C@@H](C(O)=O)CC1=CC(O)=C(O)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Rosmarinic acid
参考文献 for Rosmarinic acid
参考文献是支持产品生物活性的出版物。
Van Kessel et al (1986) Rosmarinic acid inhibits external oxidative effects of human polymorphonuclear granulocytes. Agents Actions. 17 375 PMID: 3962787
Bult et al (1985) Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid. Br.J.Pharmacol. 84 317 PMID: 3838489
Rampart et al (1986) Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid. Biochem.Pharmacol. 35 1397 PMID: 3516156
Sahu et al (1999) Inhibition of complement by covalent attachment of rosmarinic acid to activated C3b. Biochem.Pharmacol. 57 1439 PMID: 10353266
Deng et al (2012) Multiple tyrosine metabolites are GPR35 agonists. Sci.Rep. 2 373 PMID: 22523636
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关键词: Rosmarinic acid, Rosmarinic acid supplier, Anti-inflammatory, cytostatic, antiviral, GPR35, agonists, agonism, Non-selective, Antivirals, 0630, Tocris Bioscience
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