RS 09

Name: RS 09
Brand: Tocris Bioscience
SKU: 5928

Cat. No. 5928 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5928 has been discontinued.

View all Toll-like Receptors products.

说明： TLR4 peptide agonist; acts as an adjuvant in vivo

说明书

引用文献

通路 (1)

生物活性技术数据说明书参考文献

生物活性 for RS 09

RS 09 is a TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.

技术数据 for RS 09

分子量	691.78
公式	C₃₁H₄₉N₉O₉
序列	APPHALS
储存	Store at -20°C
CAS Number	1449566-36-2
PubChem ID	121513902
InChI Key	SHYNPSTXGFDOBD-HRALPVODSA-N
Smiles	[H]N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for RS 09

分析证书/产品说明书

化学品安全技术说明书

参考文献 for RS 09

参考文献是支持产品生物活性的出版物。

Li et al (2016) Intranasal vaccination against HIV-1 with adenoviral vector-based nanocomplex using synthetic TLR-4 agonist peptide as adjuvant. Mol.Pharm. 13 885 PMID: 26824411

Shanmugam et al (2012) Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. PLoS One 7 e30839 PMID: 22363498

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关键词: RS 09, RS 09 supplier, RS09, TLR4, peptides, agonists, toll-like, receptors, agonism, adjuvants, Toll-like, Receptors, 5928, Tocris Bioscience

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Pathways for RS 09

Toll-like Receptor Signaling Pathway

TLR signaling is involved in the cellular response to threatening molecules such as bacteria and viruses. It results in an inflammatory and immmunological response.