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Submit ReviewRuBi GABA trimethylphosphine is a modified version of RuBi-GABA (Cat. No. 3400). Suppresses cortical local field potential (LFP) activity in anesthetized mice after activation with a blue laser pulse (473 nm); inhibits neural activity.
Sold under licence from Columbia University
分子量 | 904.56 |
公式 | C27H33N5O2PRu.PF6.NaPF6 |
储存 | Store at -20°C |
InChI Key | AYYRUPXLUXSCBC-UHFFFAOYSA-N |
Smiles | [F-][P+5]([F-])([F-])([F-])([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-].CP(C)([Ru+2]12([N]3=CC=CC=C3C4=CC=CC=[N]14)([N]5=CC=CC=C5C6=CC=CC=[N]26)NCCCC([O-])=O)C.[Na+] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 45.23 | 50 |
以下数据基于产品分子量 904.56。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.5 mM | 2.21 mL | 11.06 mL | 22.11 mL |
2.5 mM | 0.44 mL | 2.21 mL | 4.42 mL |
5 mM | 0.22 mL | 1.11 mL | 2.21 mL |
25 mM | 0.04 mL | 0.22 mL | 0.44 mL |
参考文献是支持产品生物活性的出版物。
Lopes-dos-Santos et al (2011) In vivo photorelease of GABA in the mouse cortex. Braz.J.Med.Biol.Res. 44 688 PMID: 21755263
Filevich et al (2013) RuBiGABA-2: a hydrophilic caged GABA with long wavelength sensitivity. Photochem.Photobiol.Sci. 12 1565 PMID: 23674097
If you know of a relevant reference for RuBi GABA trimethylphosphine, please let us know.
关键词: RuBi GABA trimethylphosphine, RuBi GABA trimethylphosphine supplier, RuBi, GABA, caged, agonists, RUBIGABA2, RUBIGABA-2, RuBi-GABA-PMe3, GABAB, Receptors, GABAA, GABAA-rho, Miscellaneous, Caged, Compounds, 4709, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.