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说明： Potent PDE9 inhibitor
化学名： 6-[[(1S)-1-(4-Chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
纯度： ≥98% (HPLC)
生物活性 for (S)-C33
(S)-C33 is a potent PDE9 inhibitor (IC50 = 11 nM).
技术数据 for (S)-C33
| 分子量 | 357.84 |
| 公式 | C18H20ClN5O |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 2066488-39-7 |
| PubChem ID | 91885385 |
| InChI Key | CRRDKKMBUNVLKQ-NSHDSACASA-N |
| Smiles | C[C@@H](C1=CC=C(C=C1)Cl)NC2=NC(C3=C(N(C4CCCC4)N=C3)N2)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for (S)-C33
参考文献 for (S)-C33
参考文献是支持产品生物活性的出版物。
Huang et al (2015) Structural asymmetry of phosphodiesterase-9A and a unique pocket for selective binding of a potent enantiomeric inhibitor. Mol.Pharmacol. 88 836 PMID: 26316540
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关键词: (S)-C33, (S)-C33 supplier, phosphodiesterase, PDE9, inhibitor, Potent, SC33, Phosphodiesterases, 6035, Tocris Bioscience
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