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(S)-(-)-Carbidopa

Cat. No. 0455 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Aromatic L-amino acid decarboxylase inhibitor
化学名： (S)-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid
纯度： ≥99% (HPLC)
说明书
引用文献
评论 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for (S)-(-)-Carbidopa

(S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism.

技术数据 for (S)-(-)-Carbidopa

分子量 226.23
公式 C10H14N2O4
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 28860-95-9
PubChem ID 34359
InChI Key TZFNLOMSOLWIDK-JTQLQIEISA-N
Smiles OC1=C(O)C=CC(C[C@@](NN)(C)C(O)=O)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for (S)-(-)-Carbidopa

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 4.52 20

制备储备液 for (S)-(-)-Carbidopa

以下数据基于产品分子量 226.23。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.2 mM 22.1 mL 110.51 mL 221.01 mL
1 mM 4.42 mL 22.1 mL 44.2 mL
2 mM 2.21 mL 11.05 mL 22.1 mL
10 mM 0.44 mL 2.21 mL 4.42 mL

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产品说明书 for (S)-(-)-Carbidopa

分析证书/产品说明书
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化学品安全技术说明书

参考文献 for (S)-(-)-Carbidopa

参考文献是支持产品生物活性的出版物。

Cheng et al (1992) Carbidopa inhibition of aromatic L-amino acid decarboxylase in rat brain capilliaries. FASEB J. 6 A1589

Kopfhammer et al (1985) L-Dopa infusion experiments in combination with the L-dopa decarboxylase inhibitors benserazide and carb. - L-dopa metabolism and neuroendocrinological effects. Pharmacopsychiatry 18 143

Merck Index 12 1843

If you know of a relevant reference for (S)-(-)-Carbidopa, please let us know.

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关键词: (S)-(-)-Carbidopa, (S)-(-)-Carbidopa supplier, Aromatic, Lamino, acid, decarboxylase, inhibitors, inhibits, Decarboxylases, Dopaminergic-Related, 0455, Tocris Bioscience

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Carbidopa was used to understand it's effect on brain DDC conversion of levodopa/L-DOPA to dopamine.
By Provs Pantha on 08/16/2019
种属： Human

Carbidopa acts as a peripheral DDC inhibitor, and carbidopa was used to understand it's effect on brain DDC conversion of levodopa/L-DOPA to dopamine.

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