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Submit Review(S)-(-)-Propranolol hydrochloride is a more active enantiomer of the β-adrenoceptor antagonist propranolol.
Racemate, R-enantiomer and Glycol Metabolite also available.
分子量 | 295.81 |
公式 | C16H21NO2.HCl |
储存 | Store at RT |
纯度 | ≥98% (HPLC) |
CAS Number | 4199-10-4 |
PubChem ID | 165193 |
InChI Key | ZMRUPTIKESYGQW-UQKRIMTDSA-N |
Smiles | CC(C)NC[C@]([H])(O)COC2=CC=CC1=CC=CC=C12.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 5.92 | 20 |
以下数据基于产品分子量 295.81。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.2 mM | 16.9 mL | 84.51 mL | 169.03 mL |
1 mM | 3.38 mL | 16.9 mL | 33.81 mL |
2 mM | 1.69 mL | 8.45 mL | 16.9 mL |
10 mM | 0.34 mL | 1.69 mL | 3.38 mL |
参考文献是支持产品生物活性的出版物。
Barrett et al (1968) The biological properties of the optical isomers of propra. and their effects on cardiac arrhythmias. Br.J.Pharmacol. 34 43 PMID: 19108278
Bond et al (1967) Metabolism of propra. (Inderal) a potent, specific β-adrenergic receptor blocking agent. Nature 213 721 PMID: 6031788
If you know of a relevant reference for (S)-(-)-Propranolol hydrochloride, please let us know.
关键词: (S)-(-)-Propranolol hydrochloride, (S)-(-)-Propranolol hydrochloride supplier, β-adrenoceptor, beta-adrenoceptor, β-adrenergic, beta-adrenergic, b-adrenoceptor, b-adrenergic, antagonists, active, enantiomer, Receptors, Non-Selective, Non-selective, Adrenergic, Beta, 0834, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 (S)-(-)-Propranolol hydrochloride 的部分引用包括:
Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Br J Pharmacol 329 350 PMID: 19144685
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.