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Salmeterol

Cat. No. 1660 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

This product has been withdrawn from sale and is superseded by Salmeterol xinafoate (Cat. No. 4712)
说明： Potent β2 agonist; long acting
别名： GR 33343
化学名： 4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol
纯度： ≥99% (HPLC)
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引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for Salmeterol

Potent and selective β2-adrenoceptor agonist (EC50 = 5.3 nM); bronchodilator. Unlike other β2 agonists, binds to exo-site domain of β2 receptors, producing a slow onset of action and prolonged activation.

许可信息

Sold for research purposes under agreement from GlaxoSmithKline

技术数据 for Salmeterol

分子量 415.57
公式 C25H37NO4
储存 Store at +4°C
纯度 ≥99% (HPLC)
CAS Number 89365-50-4
Smiles Oc1ccc(C(CNCCCCCCOCCCCc2ccccc2)O)cc1CO

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Salmeterol

分析证书/产品说明书
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化学品安全技术说明书

参考文献 for Salmeterol

参考文献是支持产品生物活性的出版物。

Clark et al (1996) Stable activation and desensitization of β2-adrenergic receptor stimulation of adenylyl cyclase by salmeterol: evidence for quasi-irreversible binding to an exosite. Mol.Pharmacol. 49 182 PMID: 8569705

Ellis et al (1995) Correlation of cyclic AMP accumulation and relaxant actions of salme. and salbutamol in bovine tracheal smooth muscle. Br.J.Pharmacol. 116 2510 PMID: 8581292

Johnson et al (1993) The pharmacology of salme. Life Sci. 52 2131 PMID: 8099695

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关键词: Salmeterol, Salmeterol supplier, Potent, α2-adrenoceptor, beta2-adrenoceptor, b2-adrenoceptor, agonists, long, acting, β2-adrenergic, α2-adrenergic, beta2-adrenergic, b2-adrenergic, Receptors, GR33343, GlaxoSmithKline, GSK, GR, 33343, Adrenergic, Beta-2, 1660, Tocris Bioscience

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