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Amyloid-β (Aβ) aggregation inhibitor; blocks Aβ(1-42) aggregation and protects neuronal cell lines exposed to Aβ(1-42). Reduces Aβ oligomer-induced LTP and memory deficits in vivo.
分子量 | 322.36 |
公式 | C18H18N4O2 |
储存 | Store at +4°C |
纯度 | ≥98% (HPLC) |
CAS Number | 956128-01-1 |
PubChem ID | 46835756 |
InChI Key | MFPAAKZZUIRMKR-UHFFFAOYSA-N |
Smiles | OC1=CC(NC2=NC=C(OC3=CC=CC(N(C)C)=C3)C=N2)=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Scopes et al (2012) Aβ oligomer toxicity inhibitor protects memory in models of synaptic toxicity. Br.J.Pharmacol. 167 383 PMID: 22913627
关键词: SEN 1269, SEN 1269 supplier, SEN1269, Amyloid-β, (Aβ), aggregation, inhibitors, inhibits, LTP, memory, Alzheimer's, amyloidbeta, amyloidb, Amyloid, Beta, Peptides, 4699, Tocris Bioscience
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