主页 / 细胞生物学 / Signal Transduction / Calcium Signaling / Calcium Binding Proteins / Calcium Binding Protein Inhibitors / SGC CAMKK2-1

SGC CAMKK2-1

Cat. No. 7877 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Potent and selective CAMKK1/2 inhibitor
化学名： 2-Cyclopentyl-4-[5-(3-methylphenyl)furo[2,3-b]pyridin-3-yl]benzoic acid
纯度： ≥95% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for SGC CAMKK2-1

SGC CAMKK2-1 is a potent and selective Ca2+-calmodulin-dependent protein kinase kinase (CaMKK) inhibitor (CAMKK2 IC50 = 30 nM). Displays selectivity toward CAMKK1 and CAMKK2 over 404 kinases in a kinome wide screen (Discoverx). SGC CAMKK2-1 inhibits AMPK phosphorylation in C4-2 prostate cancer cells (IC50 = 1.6 μM).

许可信息

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC CAMKK2-1 probe summary on the SGC website.

技术数据 for SGC CAMKK2-1

分子量 397.47
公式 C26H23NO3
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2561494-76-4
PubChem ID 154700451
InChI Key TXIYVFVMXNFNRX-UHFFFAOYSA-N
Smiles O=C(C1=C(C2CCCC2)C=C(C3=COC4=NC=C(C5=CC(C)=CC=C5)C=C43)C=C1)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for SGC CAMKK2-1

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 39.75 100

制备储备液 for SGC CAMKK2-1

以下数据基于产品分子量 397.47。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.52 mL 12.58 mL 25.16 mL
5 mM 0.5 mL 2.52 mL 5.03 mL
10 mM 0.25 mL 1.26 mL 2.52 mL
50 mM 0.05 mL 0.25 mL 0.5 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for SGC CAMKK2-1

参考文献是支持产品生物活性的出版物。

Wells et al (2023) SGC-CAMKK2-1: A chemical probe for CAMKK2. Cells 12 287 PMID: 36672221

If you know of a relevant reference for SGC CAMKK2-1, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Calcium Binding Protein Inhibitors

关键词: SGC CAMKK2-1, SGC CAMKK2-1 supplier, SGCCAMKK2-1, CaM, kinase, kinases, inhibitors, inhibits, Ca2+, Calcium, Signaling, Signalling, Calmodulin, dependent, potent, selective, AMPK, Kinase, Binding, Protein, 7877, Tocris Bioscience

篇 SGC CAMKK2-1 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 SGC CAMKK2-1 的引用文献。 您是否知道使用了 Tocris SGC CAMKK2-1 的优秀论文？ 请告知我们.

SGC CAMKK2-1 的评论

目前没有该产品的评论。 Be the first to review SGC CAMKK2-1 and earn rewards!

Have you used SGC CAMKK2-1?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review