Kinases
Kinases (also known as phosphotransferases) catalyze phosphorylation. They enable the transfer of the chemically labile γ phosphoryl group from ATP or other nucleoside triphosphates to alcohol or amino group acceptors. Acceptors may be small organic molecules (e.g. glucose) or macromolecules (e.g. proteins) and the phosphorylated form of the acceptor may be more or less active than the non-phosphorylated form. Kinases are widely involved in signal transduction pathways and control complex cellular functions.
Kinase Target Files
- Abl Kinase
- Ack1
- Adenosine Kinase
- Akt (Protein Kinase B)
- AMPK
- ASK1
- ATM and ATR Kinases
- Aurora Kinases
- Bruton's Tyrosine Kinase
- CaM Kinase
- Casein Kinase 1
- Casein Kinase 2
- Checkpoint Kinases
- CLK (Cdc2-like Kinases)
- Cyclin-Dependent Kinases (CDKs)
- Death-Associated Protein Kinase
- Diacylglycerol Kinases
- DNA-Dependent Protein Kinase
- DYRK
- Focal Adhesion Kinase
- Glycogen Synthase Kinase 3
- Haspin
- Hexokinases
- IκB Kinase
- IRAK
- ITK
- JAK
- LIMK
- MAPK Family
- MEK
- MK2
- Mnk
- Monopolar Spindle 1 Kinase
- mTOR
- Myosin Light Chain Kinases
- Nek2 Kinase
- NUAKs
- P21-activated Kinases
- PERK
- PFKFB3
- Phosphoinositide-dependent Kinase 1
- PI 3-kinase
- Pim Kinase
- Polo-like Kinase
- Protein Kinase A
- Protein Kinase C
- Protein Kinase D
- Protein Kinase G
- Raf Kinases
- Receptor Interacting Protein Kinase Family
- Rho-Kinases
- RSK
- Sphingosine Kinase
- Src Kinases
- Syk Kinase
- TANK Binding Kinase
Literature for Kinases
Tocris offers the following scientific literature for Kinases to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Cancer Metabolism Research Product Guide
This product guide reviews some of the main areas in cancer metabolism research and lists around 150 products that can be used to investigate metabolic pathways in cancer including:
- Glycolysis
- Tricarboxylic Acid Cycle
- Lipidogenesis
- 1C Metabolism and Nucleic Acid Synthesis
- Drivers of Metabolic Reprogramming
- pH and Redox Balance