Sinomenine hydrochloride

Name: Sinomenine hydrochloride
Brand: Tocris Bioscience
SKU: 3848

Cat. No. 3848 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3848 has been discontinued.

View all Histaminergic-Related Compounds products.

说明： Anti-inflammatory; causes mast cell degranulation and histamine release

化学名： 9α,13α,14α -7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one hydrochloride

纯度： ≥98% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Sinomenine hydrochloride

Natural anti-inflammatory morphinan analog. Causes degranulation of mast cells in mammalian tissues to release histamine and suppresses production of proinflammatory cytokines. Also displays antinociceptive activity, possibly through activation of the μ-opioid receptor. Stimulates short-term renewal of human embryonic stem cells (ESCs) in vitro.

技术数据 for Sinomenine hydrochloride

分子量	365.85
公式	C₁₉H₂₃NO₄.HCl
储存	Store at +4°C
纯度	≥98% (HPLC)
CAS Number	6080-33-7
PubChem ID	90488887
InChI Key	YMEVIMJAUHZFMW-QKCNXVMZSA-N
Smiles	CN4C2[C@]3([H])[C@@](CC(C(OC)=C3)=O)(CC4)C1=C(O)C(OC)=CC=C1C2.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Sinomenine hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Sinomenine hydrochloride

参考文献是支持产品生物活性的出版物。

Yamasaki (1976) Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum. Acta Med.Okayama 30 1 PMID: 61710

Desbordes et al (2008) High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell 2 602 PMID: 18522853

Wang et al (2008) Activation of opioid μ-receptor by sinomenine in cell and mice. Neurosci.Lett. 443 209 PMID: 18692550

Qian et al (2007) Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase. J.Neuroinflamm. 4 23

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