SKF 91488 dihydrochloride

Discontinued Product

0512 has been discontinued.

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说明: Histamine N-methyltransferase inhibitor
化学名: 4-(N,N-Dimethylamino)butylisothiourea dihydrochloride
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生物活性 for SKF 91488 dihydrochloride

SKF 91488 dihydrochloride is a homolog of dimaprit (Cat. No. 0506); strong inhibitor of histamine N-methyltransferase. Exhibits no histamine agonist activity.

技术数据 for SKF 91488 dihydrochloride

分子量 248.21
公式 C7H17N3S.2HCl
储存 Desiccate at RT
CAS Number 68941-21-9
PubChem ID 11957708
InChI Key NPLHSMBWWIIWAQ-UHFFFAOYSA-N
Smiles CN(CCCCSC(=N)N)C.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for SKF 91488 dihydrochloride

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参考文献 for SKF 91488 dihydrochloride

参考文献是支持产品生物活性的出版物。

Aiello et al (1997) Effects of two histamine-N-methyltransferase inhibitors, SKF 91488 and BW 301U, in rodent antinociception. Naunyn Schmiedebergs Arch.Pharmacol. 355 354 PMID: 9089666

Beaven and Shaff (1979) New inhibitors of histamine N-methyl-transferase. Biochem.Pharmacol. 28 183 PMID: 34400

Beaven and Shaff (1979) Inhibition of histamine methylation in vivo by the dimaprit analog SKF compound 91488. Agents Actions 9 455 PMID: 161853

Ohuri et al (1992) Histamine N-methyl transferase controls the contractile response of guinea pig trachea to histamine. J.Pharmacol.Exp.Ther. 261 1268 PMID: 1534842

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关键词: SKF 91488 dihydrochloride, SKF 91488 dihydrochloride supplier, Histamine, N-methyltransferase, inhibitors, inhibits, transferases, Histaminergic-related, Compounds, Receptors, SKF91488, dihydrochloride, Other, Transferases, Histaminergic-Related, 0512, Tocris Bioscience

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