SMANT hydrochloride

Name: SMANT hydrochloride
Brand: Tocris Bioscience
SKU: 4662

Cat. No. 4662 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4662 has been discontinued.

View all Smoothened Receptors products.

说明： Inhibits Smoothened (Smo) accumulation

化学名： N-(4-Bromophenyl)-3,5-dimethyl-1-piperidinepropanamide hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for SMANT hydrochloride

SMANT hydrochloride is an inhibitor of Smoothened (Smo) signaling via a unique mechanism. Inhibits Shh-induced accumulation of Smo::EGFP fusion protein in the primary cilium (IC₅₀ = 1.1 μM). Inhibits both wild-type Smo and an oncogenic form (SmoM2) with similar efficacy.

技术数据 for SMANT hydrochloride

分子量	375.73
公式	C₁₆H₂₃BrN₂O.HCl
储存	Desiccate at RT
纯度	≥99% (HPLC)
CAS Number	1177600-74-6
PubChem ID	2900213
InChI Key	XQESCHFXROUCOQ-UHFFFAOYSA-N
Smiles	BrC1=CC=C(NC(CCN2CC(C)CC(C)C2)=O)C=C1.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for SMANT hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for SMANT hydrochloride

参考文献是支持产品生物活性的出版物。

Wang et al (2012) Selective identification of Hedgehog pathway antagonists by direct analysis of Smoothened ciliary translocation. ACS Chem.Biol. 7 1040 PMID: 22554036

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篇 SMANT hydrochloride 的引用文献

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