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说明： Selective TRPML3 channel activator
化学名： 3a,4,5,6,7,7a-Hexahydro-3-(2,4,6-trimethylphenyl)-4,7-methano-1,2-benzisoxazole
纯度： ≥98% (HPLC)
生物活性 for SN 2
SN 2 is a selective TRPML3 channel activator (EC50 = 1.13 μM).
化合物库 for SN 2
SN 2 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。
技术数据 for SN 2
| 分子量 | 255.35 |
| 公式 | C17H21NO |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 823218-99-1 |
| PubChem ID | 11834987 |
| InChI Key | WKLZNTYMDOPBSE-UHFFFAOYSA-N |
| Smiles | CC1=CC(C)=CC(C)=C1C2=NOC3C2C4CCC3C4 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for SN 2
参考文献 for SN 2
参考文献是支持产品生物活性的出版物。
Grimm et al (2010) Small molecule activators of TRPML3. Chem.Biol. 17 135 PMID: 20189104
Jörs (2010) Genetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in mice. PLoS ONE 5 e14317 PMID: 21179200
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关键词: SN 2, SN 2 supplier, Selective, TRPML3, channels, activators, SN2, transient, receptor, potential, activates, TRPML, 4907, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Autophagy Scientific Review
Written by Patricia Boya and Patrice Codogno, this review summarizes the molecular mechanisms, physiology and pathology of autophagy. The role of autophagy in cell death and its links to disease are also discussed. Compounds available from Tocris are listed.
Autophagy Poster
Autophagy is a cellular process used by cells for degradation and recycling. Written by Patricia Boya and Patrice Codogno, this poster summarizes the molecular machinery, physiology and pathology of autophagy. Compounds available from Tocris are listed.