Sodium orthovanadate

Cat. No. 2821 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Protein tyrosine phosphatase inhibitor

化学名： Trisodium vanadate

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Sodium orthovanadate

Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases. Suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.

技术数据 for Sodium orthovanadate

分子量	183.91
公式	Na₃O₄V
储存	Store at RT
CAS Number	13721-39-6
PubChem ID	61671
InChI Key	IHIXIJGXTJIKRB-UHFFFAOYSA-N
Smiles	O=[V]([O-])([O-])[O-].[Na+].[Na+].[Na+]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Sodium orthovanadate

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	18.39	100

制备储备液 for Sodium orthovanadate

以下数据基于产品分子量 183.91。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	5.44 mL	27.19 mL	54.37 mL
5 mM	1.09 mL	5.44 mL	10.87 mL
10 mM	0.54 mL	2.72 mL	5.44 mL
50 mM	0.11 mL	0.54 mL	1.09 mL

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产品说明书 for Sodium orthovanadate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Sodium orthovanadate

参考文献是支持产品生物活性的出版物。

Ai et al (2004) Inhibition of small-intestinal sugar absorption mediated by sodium orthovanadate Na₃VO₄ in rats and its mechanisms. World J.Gastroenterol. 10 3612 PMID: 15534916

Hasegawa et al (2006) Therapeutic time window and dose dependence of neuroprotective effects of sodium orthovanadate following transient middle cerebral artery occlusion in rats. J.Pharmacol.Exp.Ther. 317 875 PMID: 16461588

Matsumoto et al (2006) Sodium orthovanadate enhances proliferation of progenitor cells in the adult rat subventricular zone after focal cerebral ischemia. J.Pharmacol.Exp.Ther. 318 982 PMID: 16782823

Morita et al (2010) Sodium orthovanadate inhibits p53-mediated apoptosis. Cancer Res. 70 257 PMID: 20048077

If you know of a relevant reference for Sodium orthovanadate, please let us know.

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关键词: Sodium orthovanadate, Sodium orthovanadate supplier, Protein, tyrosine, phosphatase, inhibitors, PTP, Shp1, Shp2, Tyrosine, Phosphatases, inhibits, ATPases, inhibitor, alkaline, phosphatases, Other, 2821, Tocris Bioscience

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