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Submit ReviewSomatostatin is an endogenous peptide; inhibits the release of growth hormone, insulin and glucagon. Inhibits voltage-dependent calcium channels.
分子量 | 1637.88 |
公式 | C76H104N18O19S2 |
序列 |
AGCKNFFWKTFTSC (Modification: Disulfide bridge: 3-14) |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 51110-01-1 |
PubChem ID | 16129706 |
InChI Key | NHXLMOGPVYXJNR-ATOGVRKGSA-N |
Smiles | [H]N[C@@H](C)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC1=O)[C@@H](C)O)[C@@H](C)O)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性 | Soluble to 0.30 mg/ml in water |
参考文献是支持产品生物活性的出版物。
Alderton et al (1998) Differential effects of somatostatin and angiopeptin on cell proliferation. Br.J.Pharmacol. 124 323 PMID: 9641549
Dileepan et al (1985) Somatostatin: a metabolic regulator. Life Sci. 37 2335 PMID: 2867445
Ohmura et al (1990) Somatostatin decreases the calcium inward current in guinea-pig atria. Br.J.Pharmacol. 99 587 PMID: 1970502
If you know of a relevant reference for Somatostatin, please let us know.
关键词: Somatostatin, Somatostatin supplier, Influences, growth, hormone, release, sst, Receptors, Somatostatin, 1157, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Somatostatin 的部分引用包括:
Kothegala et al (2023) Somatostatin Containing δ-Cell Number Is Reduced in Type-2 Diabetes Int J Mol Sci 24 3449
Chiu et al (2013) Bacteria activate sensory neurons that modulate pain and inflammation. Nature 501 52 PMID: 23965627
Akoume et al (2019) A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression. Sci Rep 9 10074 PMID: 31296888
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