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SR 11237

Cat. No. 3411 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Pan RXR agonist
别名： BMS 649
化学名： 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dioxolan-2-yl]-benzoic acid
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for SR 11237

SR 11237 is a pan retinoid X receptor (RXR) agonist that is devoid of any RAR activity.

化合物库 for SR 11237

SR 11237 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for SR 11237

分子量 380.48
公式 C24H28O4
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 146670-40-8
PubChem ID 127019
InChI Key ZZUKALQMHNSWTK-UHFFFAOYSA-N
Smiles CC1(C)C2=C(C=CC(C4(OCCO4)C3=CC=C(C(O)=O)C=C3)=C2)C(C)(C)CC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for SR 11237

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 38.05 100

制备储备液 for SR 11237

以下数据基于产品分子量 380.48。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.63 mL 13.14 mL 26.28 mL
5 mM 0.53 mL 2.63 mL 5.26 mL
10 mM 0.26 mL 1.31 mL 2.63 mL
50 mM 0.05 mL 0.26 mL 0.53 mL

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产品说明书 for SR 11237

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for SR 11237

参考文献是支持产品生物活性的出版物。

Chiba et al (1997) Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells. Mol.Cell.Biol. 17 3013 PMID: 9154799

Benoit et al (1999) RAR-independent RXR signaling induces t(15;17) leukemia cell maturation. EMBO J. 18 7011 PMID: 10601023

Zhou et al (2010) Retinoid X receptor agonists inhibit phorbol-12-myristate-13-acetate (PMA)-induced differentiation of monocytic THP-1 cells into macrophages. Mol.Cell.Biochem. 335 283 PMID: 19784811

If you know of a relevant reference for SR 11237, please let us know.

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关键词: SR 11237, SR 11237 supplier, SR11237, BMS649, retinoid, X, receptors, agonist, pan, RXR, RXRalpha, RTXRbeta, RXRgamma, RXRg, RXRa, RXRb, RXRα, RXRβ, RXRγ, BMS, 649, Retinoid, Receptor, 3411, Tocris Bioscience

1 篇 SR 11237 的引用文献

引用文献是使用了 Tocris 产品的出版物。 SR 11237 的部分引用包括：

Halstead et al (2017) Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation. Elife 6 PMID: 29143738

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SR 11237 的评论

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Retinoid Receptors Scientific Review

Retinoid Receptors Scientific Review

Written by Alexander Moise, this review summarizes the nature of retinoid receptors, their isotype and isoform variants and modulation of retinoid signaling. Compounds available from Tocris are listed.