SR 57227 hydrochloride

Name: SR 57227 hydrochloride
Brand: Tocris Bioscience
SKU: 1205
Rating: 4 (1 reviews)

Cat. No. 1205 1 次引用 1 条评论提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Potent and selective 5-HT₃ agonist

化学名： 1-(6-Chloro-2-pyridinyl)-4-piperidinamine hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献 (1)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for SR 57227 hydrochloride

SR 57227 hydrochloride is a high affinity, selective 5-HT₃ receptor agonist, active in vivo and CNS penetrant.

技术数据 for SR 57227 hydrochloride

分子量	248.15
公式	C₁₀H₁₄ClN₃.HCl
储存	Store at RT
纯度	≥99% (HPLC)
CAS Number	77145-61-0
PubChem ID	131746
InChI Key	FUMINTAAUJUVMP-UHFFFAOYSA-N
Smiles	Cl.NC1CCN(CC1)C1=NC(Cl)=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for SR 57227 hydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	water	24.82	100
	DMSO	24.82	100

制备储备液 for SR 57227 hydrochloride

以下数据基于产品分子量 248.15。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	4.03 mL	20.15 mL	40.3 mL
5 mM	0.81 mL	4.03 mL	8.06 mL
10 mM	0.4 mL	2.01 mL	4.03 mL
50 mM	0.08 mL	0.4 mL	0.81 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

产品说明书 for SR 57227 hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for SR 57227 hydrochloride

参考文献是支持产品生物活性的出版物。

Bachy et al (1993) SR 57227A: a potent and selective agonist at central and peripheral 5-HT₃ receptors in vitro and in vivo. Eur.J.Pharmacol. 237 299 PMID: 7689975

Edwards et al (1996) 5-HT₃-like receptors in the rat medial prefrontal cortex: further pharmacological characterization. Brain Res. 733 21 PMID: 8891244

If you know of a relevant reference for SR 57227 hydrochloride, please let us know.

按标靶查看相关产品

5-HT₃ Receptors

按产品操作查看相关产品

查看全部 5-HT₃ Receptor Agonists

关键词: SR 57227 hydrochloride, SR 57227 hydrochloride supplier, Potent, selective, 5-HT3, agonists, Serotonin, Receptors, SR57227, hydrochloride, 1205, Tocris Bioscience

1 篇 SR 57227 hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 SR 57227 hydrochloride 的部分引用包括：

Otvos et al (2015) Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Dent Res J (Isfahan) 7 2336 PMID: 26114334

您是否知道使用了 Tocris SR 57227 hydrochloride 的优秀论文？请告知我们.

SR 57227 hydrochloride 的评论

平均评分: 4 (Based on 1 Review.)

5 星

4 星

100%

3 星

2 星

1 星

Have you used SR 57227 hydrochloride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:

PGE2 release.

By jialie luo on 01/10/2018

分析类型： In Vitro

种属： Mouse

SR 57227 hydrochloride was used to stimulate macrophages as negative control.

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.