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Submit ReviewStavudine
说明： Inhibis HIV-1 replication in vitro; nucleoside analog
化学名： 1-[(2R,5S)-2,5-Dihydro-5-(hydroxymethyl)-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
纯度： ≥99% (HPLC)
生物活性 for Stavudine
Stavudine is a nucleoside analog; antiviral that inhibits HIV replication in vitro. Orally bioavailable.
化合物库 for Stavudine
Stavudine is also offered as part of the Tocriscreen FDA-Approved Drugs. 了解 Tocris 化合物库的更多信息。
技术数据 for Stavudine
| 分子量 | 224.21 |
| 公式 | C10H12N2O4 |
| 储存 | Store at -20°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 3056-17-5 |
| PubChem ID | 18283 |
| InChI Key | XNKLLVCARDGLGL-JGVFFNPUSA-N |
| Smiles | [H]C1=C([H])[C@@H](O[C@@H]1CO)N1C=C(C)C(=O)NC1=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Stavudine
参考文献 for Stavudine
参考文献是支持产品生物活性的出版物。
Baba et al (1987) Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro. Biochem.Biophys.Res.Commun. 142 128 PMID: 3028398
Riddler et al (1995) Antiretroviral activity of stav. (2',3'-didehydro-3'-deoxythymidine, D4T). Antiviral Res. 27 189 PMID: 8540743
关键词: Stavudine, Stavudine supplier, Nucleoside, analogues, inhibits, HIV, replication, antiviral, 2,3-Didehydro-3-deoxythymidine, DNA,, RNA, and, Protein, Synthesis, 4990, Tocris Bioscience
Stavudine 的评论
平均评分: 4 (Based on 1 Review.)
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Stavudine was studied to understand how it affects cellular synthesis of mitochondrial DNA.
By
Anonymous on 11/30/2019
种属： Human
Stavudine triphosphate was studied to understand how it affects cellular synthesis of mitochondrial DNA.
Cells were grown and differentiated, as described in the text, in the presence of 0, 1, or 10 μM AZT.
