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说明： EP3 and EP1 receptor agonist
化学名： (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide
生物活性 for Sulprostone
Sulprostone is a selective EP3 and EP1 receptor agonist (Ki values are 0.6 and 21 nM respectively). Synthetic PGE2 analog and allodynic agent.
技术数据 for Sulprostone
| 分子量 | 465.56 |
| 公式 | C23H31NO7S |
| 储存 | Store at -20°C |
| CAS Number | 60325-46-4 |
| PubChem ID | 5312153 |
| InChI Key | UQZVCDCIMBLVNR-TWYODKAFSA-N |
| Smiles | O=C1[C@H](C/C=C\CCCC(NS(=O)(C)=O)=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC=C2)[C@H](O)C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Sulprostone
参考文献 for Sulprostone
参考文献是支持产品生物活性的出版物。
Gil et al (2008) Transient allodynia pain models in mice for assessment of analgesic activity. Br.J.Pharmacol. 153 769 PMID: 17700719
Narumiya et al (1999) Prostanoid receptors: Structures, properties, and functions. Phys.Rev. 79 1193
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关键词: Sulprostone, Sulprostone supplier, Sulprostone, prostaglandin, prostanoid, EP1, EP3, receptor, agonist, Prostanoid, Receptors, 3049, Tocris Bioscience
1 篇 Sulprostone 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Sulprostone 的部分引用包括：
Ye et al (2018) Prostaglandin E2 receptor 3 signaling is induced in placentas with unexplained recurrent pregnancy losses. Endocr Connect 7 749 PMID: 29700097
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