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说明： Basic fibroblast growth factor (bFGF) mimetic; neuroprotective
化学名： 4-[[4-[[2-[(4-Amino-2,3,5,6-tetramethylphenyl)amino]acetyl]methylamino]-1-piperidinyl]methyl]benzamide
纯度： ≥98% (HPLC)
生物活性 for SUN 11602
SUN 11602 is a basic fibroblast growth factor (bFGF) mimetic. Mimics the neuroprotective effects of bFGF; prevents glutamate-induced neuronal death. Increases levels of CALB1 gene expression in cerebrocortical neurons. Triggers phosphorylation of FGFR, ERK1 and ERK2.
技术数据 for SUN 11602
| 分子量 | 451.61 |
| 公式 | C26H37N5O2 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 704869-38-5 |
| PubChem ID | 22245705 |
| InChI Key | KCODNOOPOPTZMO-UHFFFAOYSA-N |
| Smiles | NC1=C(C)C(C)=C(NCC(N(C)C2CCN(CC3=CC=C(C(N)=O)C=C3)CC2)=O)C(C)=C1C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for SUN 11602
参考文献 for SUN 11602
参考文献是支持产品生物活性的出版物。
Murayama et al (2013) SUN11602, a novel aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. ACS Chem.Neurosci. 4 266 PMID: 23421678
关键词: SUN 11602, SUN 11602 supplier, SUN11602, basic, fibroblast, growth, factor, bFGF, calcium, binding, protein, calbindin-D28k, Calb, FGFR, receptor, ERK1, ERK2, 4826, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Stem Cell Research Product Guide
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- Organoid Generation
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Stem Cells Scientific Review
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
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