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说明： Very high affinity FP receptor agonist
化学名： 1-Methylethyl (5-Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoate
纯度： ≥95% (HPLC)
生物活性 for Tafluprost
Tafluprost is a very high affinity FP receptor agonist (Ki = 0.4 nM). Reduces intraocular pressure (IOP) in animal models of ocular hypertension and normal animals.
技术数据 for Tafluprost
| 分子量 | 452.53 |
| 公式 | C25H34F2O5 |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 209860-87-7 |
| PubChem ID | 9868491 |
| InChI Key | WSNODXPBBALQOF-VEJSHDCNSA-N |
| Smiles | O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/C(F)(F)COC2=CC=CC=C2)[C@H](O)C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Tafluprost
参考文献 for Tafluprost
参考文献是支持产品生物活性的出版物。
Takagi et al (2004) Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug. Exp.Eye Res. 78 767 PMID: 15037111
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关键词: Tafluprost, Tafluprost supplier, AFP-168, AFP168, ocular, hypertension, very, high, afifinity, FP, agonists, agonism, prostaglandins, IOP, Prostanoid, Receptors, 6427, Tocris Bioscience
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