Talopram hydrochloride

Name: Talopram hydrochloride
Brand: Tocris Bioscience
SKU: 3145

Cat. No. 3145 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3145 has been discontinued.

View all Adrenergic Transporters products.

说明： Potent, selective inhibitor of noradrenalin transporters

别名： Lu 3-010

化学名： 1,3-Dihydro-N,3,3-trimethyl-1-phenyl-1-isobenzofuranpropanamine hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Talopram hydrochloride

Talopram hydrochloride is a potent, selective inhibitor of the noradrenalin transporter (NET) (IC₅₀ = 2.9 nM). Exhibits selectivity for NET against SERT (5-HT transporters) and DAT (dopamine transporters). Displays a similar structure but different pharmacological profile to citalopram (Cat. No. 1427).

技术数据 for Talopram hydrochloride

分子量	331.88
公式	C₂₀H₂₅NO.HCl
储存	Desiccate at RT
纯度	≥99% (HPLC)
CAS Number	7013-41-4
PubChem ID	71176
InChI Key	JZXJIRQPHHWYGC-UHFFFAOYSA-N
Smiles	CC2(C)OC(C3=CC=CC=C3)(CCCNC)C1=CC=CC=C12.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Talopram hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Talopram hydrochloride

参考文献是支持产品生物活性的出版物。

Bogeso et al (1985) 3-phenyl-1-indanamines. Potential antidepressant activity and potent inhibition of DA, NE, and serotonin uptake. J.Med.Chem. 28 1817 PMID: 2999402

Eildal et al (2008) From the selective serotonin transporter inhibitor cital. to the selective NE transporter inhibitor talopram: synthesis and structure-activity relationship studies. J.Med.Chem. 51 3045 PMID: 18429609

Schou et al (2006) Synthesis and positron emission tomography evaluation of three NE transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram. Mol.Imaging Biol. 8 1

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篇 Talopram hydrochloride 的引用文献

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