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Submit ReviewTaltirelin
Discontinued Product
2672 has been discontinued.
View all Thyrotropin-Releasing Hormone Receptors products.
说明： Synthetic thyrotropin-releasing hormone analog
别名： TA 0910
化学名： N-[[(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl]carbonyl]-L-histidyl-L-prolinamide
纯度： ≥96% (HPLC)
生物活性 for Taltirelin
Taltirelin is a synthetic thyrotropin-releasing hormone (TRH) analog. Displays ~ 30 - 100-fold more potent CNS activity and ~ 50-fold weaker endocrine activity than TRH. Antinociceptive and neuroprotective.
技术数据 for Taltirelin
| 分子量 | 405.41 |
| 公式 | C17H23N7O5 |
| 储存 | Store at -20°C |
| 纯度 | ≥96% (HPLC) |
| CAS Number | 103300-74-9 |
| PubChem ID | 114750 |
| InChI Key | LQZAIAZUDWIVPM-SRVKXCTJSA-N |
| Smiles | CN(C(C[C@@H]([C@@](N[C@@H](CC3=CNC=N3)C(N2[C@H]([C@](N)=O)CCC2)=O)=O)N1)=O)C1=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Taltirelin
参考文献 for Taltirelin
参考文献是支持产品生物活性的出版物。
Suzuki et al (1990) Synthesis and central nervous system actions of thyrotropin-releasing hormone analogues containing a dihydroorotic acid moiety. J.Med.Chem. 33 2130 PMID: 2115588
Urayama et al (2002) Neuroprotective effect and brain receptor binding of taltirelin, a novel thyrotropin-releasing hormone (TRH) analogue, in transient forebrain ischemia of C57BL/6J mice. Life Sci. 72 601 PMID: 12467901
Tanabe et al (2007) The synthetic TRH analogue taltirelin exerts modality-specific antinociceptive effects via distinct descending monoaminergic systems. Br.J.Pharmacol. 150 403 PMID: 17220907
关键词: Taltirelin, Taltirelin supplier, Synthetic, thyrotropin-releasing, hormone, TRH, Receptors, TA0910, TA, 0910, Thyrotropin-Releasing, Hormone, 2672, Tocris Bioscience
1 篇 Taltirelin 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Taltirelin 的部分引用包括：
Thirunarayanan et al (2012) Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor. PeerJ 3 120 PMID: 23087672
Taltirelin 的评论
平均评分: 5 (Based on 1 Review.)
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good quality.
By
Anonymous on 01/05/2018
分析类型： Ex Vivo
种属： Mouse
calcium imaging