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说明： High affinity and potent CB1 inverse agonist
化学名： [2-(2,4-Dichlorophenyl)-6-fluoro-2-(4-fluorophenyl)-1,3-benzodioxol-5-yl]-4-morpholinyl-methanone
纯度： ≥98% (HPLC)
生物活性 for TC-C 14G
TC-C 14G is a potent, high affinity CB1 receptor inverse agonist (EC50 = 11 nM in cAMP assay; Ki = 4 nM). Demonstrates high efficacy in a hypothermia assay (ID50 = 5 mg/kg) in vivo.
技术数据 for TC-C 14G
| 分子量 | 492.3 |
| 公式 | C24H17Cl2F2NO4 |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 656804-72-7 |
| PubChem ID | 22475020 |
| InChI Key | VUCKSZWMRCSPME-UHFFFAOYSA-N |
| Smiles | FC1=CC2=C(OC(C3=C(Cl)C=C(Cl)C=C3)(C4=CC=C(F)C=C4)O2)C=C1C(N5CCOCC5)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for TC-C 14G
参考文献 for TC-C 14G
参考文献是支持产品生物活性的出版物。
Alig et al (2008) Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity. J.Med.Chem. 51 2115 PMID: 18335976
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关键词: TC-C 14G, TC-C 14G supplier, TC-C14G, cannabinoid, CB1, receptor, inverse, agonists, potent, high, affinity, Receptors, 4345, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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