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TC-O 9311

Cat. No. 4255 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4255 has been discontinued.

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说明： Potent and selective GPR139 agonist
化学名： 3,5-Dimethoxybenzoic acid 2-[(1-naphthalenylamino)carbonyl]hydrazide
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for TC-O 9311

TC-O 9311 is a potent GPR139 agonist (EC50 = 39 nM in CHO-K1 cells expressing human GPR139). Displays no activity against a range of 90 diverse targets.

化合物库 for TC-O 9311

TC-O 9311 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for TC-O 9311

分子量 365.38
公式 C20H19N3O4
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 444932-31-4
PubChem ID 3376937
InChI Key KPTMSQHTGZMEFU-UHFFFAOYSA-N
Smiles O=C(NNC(NC2=CC=CC3=C2C=CC=C3)=O)C1=CC(OC)=CC(OC)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for TC-O 9311

参考文献是支持产品生物活性的出版物。

Shi et al (2011) Discovery and SAR of a series of agonists at orphan G protein-coupled receptor 139. ACS Med.Chem.Lett. 2 303 PMID: 24900311

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关键词: TC-O 9311, TC-O 9311 supplier, TCO9311, gpr139, receptors, orphan, potent, selective, agonists, Orphan, 7-TM, Receptors, 4255, Tocris Bioscience

1 篇 TC-O 9311 的引用文献

引用文献是使用了 Tocris 产品的出版物。 TC-O 9311 的部分引用包括：

Nepomuceno et al (2018) Re-evaluation of Adrenocorticotropic Hormone and Melanocyte Stimulating Hormone Activation of GPR139 in Vitro. Front Pharmacol 9 157 PMID: 29599718

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