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Submit ReviewTetraethylammonium chloride is a non-selective K+ channel blocker.
分子量 | 165.2 |
公式 | C8H20ClN |
储存 | Desiccate at RT |
CAS Number | 56-34-8 |
PubChem ID | 5946 |
InChI Key | YMBCJWGVCUEGHA-UHFFFAOYSA-M |
Smiles | CC[N+](CC)(CC)CC.[Cl-] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
water | 100 |
以下数据基于产品分子量 165.2。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 6.05 mL | 30.27 mL | 60.53 mL |
5 mM | 1.21 mL | 6.05 mL | 12.11 mL |
10 mM | 0.61 mL | 3.03 mL | 6.05 mL |
50 mM | 0.12 mL | 0.61 mL | 1.21 mL |
参考文献是支持产品生物活性的出版物。
Niu et al (2008) Vasorelaxant effect of taurine is diminished by tetraethylammonium in rat isolated arteries. Eur.J.Pharmacol. 580 169 PMID: 17997400
If you know of a relevant reference for Tetraethylammonium chloride, please let us know.
关键词: Tetraethylammonium chloride, Tetraethylammonium chloride supplier, Non-Selective, K+, channels, blockers, Potassium, TEA, Voltage-Gated, Channels, 3068, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Tetraethylammonium chloride 的部分引用包括:
Lerner et al (2010) Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. J Neurosci 30 2160 PMID: 20147543
Collins et al (2018) Reciprocal Circuits Linking the Prefrontal Cortex with Dorsal and Ventral Thalamic Nuclei. Neuron 98 366 PMID: 29628187
Borgs et al (2016) DArgic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Scientific Reports 6 33377 PMID: 27640816
Chanda et al (2014) Generation of induced neuronal cells by the single reprogramming factor ASCL1. Sleep 3 282 PMID: 25254342
Grace et al (2014) Identification of a pharmacological target for genioglossus reactivation throughout sleep. Iran J Pharm Res 37 41 PMID: 24470694
Chanda et al (2013) Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. Stem Cell Reports 110 16622 PMID: 24046374
Zhang et al (2019) A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells. J Biol Chem PMID: 30792309
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Tetraethylammonium was used to identify percentage blocking on potassium channel.The product shows relatively low blocking action on potassium channels. It works good on sterile conditions and the data pattern is quite similar.