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Submit ReviewTetrindole mesylate
说明： MAO-A inhibitor
化学名： 2,3,3a,4,5,6-Hexahydro-8-cyclohexyl-1H-pyrazino[3,2,1-j,k]carbazole mesylate
纯度： ≥99% (HPLC)
生物活性 for Tetrindole mesylate
Tetrindole mesylate is a novel antidepressant, a selective inhibitor of MAO-A.
技术数据 for Tetrindole mesylate
| 分子量 | 390.54 |
| 公式 | C20H26N2.CH3SO3H |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 170964-68-8 |
| PubChem ID | 54792409 |
| InChI Key | CWPNPYVNPOAMHY-UHFFFAOYSA-N |
| Smiles | CS(O)(=O)=O.C1CCC(CC1)C1=CC=C2N3CCNC4CCCC(=C34)C2=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Tetrindole mesylate
参考文献 for Tetrindole mesylate
参考文献是支持产品生物活性的出版物。
Bos et al (1995) Resolution, EPC-syntheses, absolute stereochemistry, and pharmacology of the (S)-(+)- and (R)-(-)-isomers of the MAO-A inhibitor tetrindole hydrochloride. Arch.Pharm. (Wenheim) 328 619 PMID: 7492268
Korshunov et al (2000) Hemodynamic effects of tetrindol in alert normotensive mice and rats after blockade of nitric oxide synthesis. Bull.Exp.Biol.Med. 130 777 PMID: 11177242
Medvedev et al (1994) Monoamine oxidase inhibition by novel antidepressant tetrindole. Biochem.Pharmacol. 47 303 PMID: 8304974
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关键词: Tetrindole mesylate, Tetrindole mesylate supplier, MAO-A, inhibitors, inhibits, Monoamine, Oxygenases, Oxidases, Oxidase, Adrenergic, Related, Compounds, Dopaminergic-Related, 5-HT-Related, 5-HT3, Receptors, 0723, Tocris Bioscience
1 篇 Tetrindole mesylate 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Tetrindole mesylate 的部分引用包括：
Ulferts et al (2016) Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C. Antimicrob Agents Chemother 60 2627 PMID: 26856848
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.
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Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.