TFAX 546, SE

Discontinued Product

6623 has been discontinued.

View all TFAX (AF) Dyes products.
说明: Yellow fluorescent dye; amine reactive
化学名: 6-[2-Carboxy-3,4,6-trichloro-5-[[2-[[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]amino]-2-oxoethyl]thio]phenyl]-1,2,3,4,8,9,10,11-octahydro-2,2,4,8,10,10-hexamethyl-12,14-disulfopyrano[3,2-g:5,6-g']diquinolin-13-ium triethylammonium salt
说明书
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生物活性 for TFAX 546, SE

TFAX 546, SE is an amine reactive yellow fluorescent dye. Insensitive to pH in the range 4 - 10. Forms bright and photostable conjugates with proteins and antibodies. Suitable for use in microscopy. Excitation maximum = 554 nm; emission maximum = 570 nm; extinction coefficient = 112,000 M-1cm-1; quantum yield = 0.79.

Optical Data for TFAX 546, SE

TFAX 546, SE Dye Spectra
Emission Color Yellow
Brightness
λabs 554 nm
λem 570 nm
Extinction Coefficient (ε) 112000 M-1cm-1
Quantum Yield (φ) 0.79
Closest Laser line 532 nm
Reactive Group NHS ester
Reactivity Primary amines
Cell Permeable No
pH Sensitivity pH insensitive pH 4-10
Application microscopy
Alternative For TMR, Cyanine3, Alexa Fluor 546 SE, AF 546 SE

Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company.

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技术数据 for TFAX 546, SE

分子量 1159.6
公式 C44H47Cl3N4O14S.(CH3CH2)3NH
储存 Store at -20°C
Smiles ClC(C(Cl)=C1C(O)=O)=C(SCC(NCCCCCC(ON2C(CCC2=O)=O)=O)=O)C(Cl)=C1C(C3=CC4=C(NC(C)(C)CC4C)C(S(=O)([O-])=O)=C3O5)=C6C5=C(S(=O)([O-])=O)C7=[NH+]C(C)(C)CC(C)C7=C6.CC[NH+](CC)CC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for TFAX 546, SE

参考文献是支持产品生物活性的出版物。

Hone et al (2010) Alexa Fluor 546-ArIB[V11L;V16A] is a potent ligand for selectively labeling α 7 nicotinic acetylcholine receptors. J.Neurochem. 114 994 PMID: 20492354

Iwata et al (2005) Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation. Proc.Natl.Acad.Sci.USA. 102 13135 PMID: 16141322

Panchuk-Voloshina et al (1999) Alexa dyes, a series of new fluorescent dyes that yield exceptionally bright, photostable conjugates. J.Histochem.Cytochem. 47 1179 PMID: 10449539

关键词: TFAX 546, SE, TFAX 546, SE supplier, TFAX546,, SE, TFAX546SE, Amine, reactive, yellow, fluorescent, dye, microscopy, flow, cytometry, CAS, 477876-66-7, TFAX, Dyes, Flow, Cytometry, 6623, Tocris Bioscience

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