TFMPP hydrochloride

Discontinued Product

0968 has been discontinued.

View all 5-HT<sub>1B</sub> Receptors products.
说明: 5-HT1B partial agonist
化学名: N-(3-Trifluoromethylphenyl)piperazine hydrochloride
纯度: ≥99% (HPLC)
说明书
引用文献
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文献 (2)

生物活性 for TFMPP hydrochloride

Partial agonist with some preference for 5-HT1B receptors; displays similar potency at 5-HT1A and 5-HT2C receptors.

技术数据 for TFMPP hydrochloride

分子量 266.69
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 16015-69-3

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Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for TFMPP hydrochloride

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参考文献 for TFMPP hydrochloride

参考文献是支持产品生物活性的出版物。

Chaouloff et al (1998) GR 127935 and (+)-WAY 100135 do not affect TFMPP-induced inhibition of 5-HT synthesis in the midbrain and hippocampus of Wistar-Kyoto rats. Neuropharmacology 37 1159 PMID: 9833646

Lucki et al (1989) Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine on locomotor activity. J.Pharmacol.Exp.Ther. 249 155 PMID: 2709329

Schoeffter and Hoyer (1989) Interaction of arylpiperazines with 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors: do discriminatory 5-HT1B receptor ligands exist? Naunyn Schmiedebergs Arch.Pharmacol. 339 675 PMID: 2770889

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关键词: TFMPP hydrochloride, TFMPP hydrochloride supplier, 5-HT1B, Receptors, 5-HT-Related, 0968, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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5-HT Receptors Scientific Review

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Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.