Thrombin Receptor Agonist Peptide

Cat. No. 1185 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Causes platelet aggregation and secretion

别名： TRAP

纯度： ≥95% (HPLC)

引用文献 (2)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Thrombin Receptor Agonist Peptide

Thrombin Receptor Agonist Peptide is an agonist at the thrombin receptor; causes platelet aggregation (EC₅₀ = 4 μM) and secretion.

技术数据 for Thrombin Receptor Agonist Peptide

分子量	1739.95
公式	C₈₁H₁₁₈N₂₀O₂₃
序列	SFLLRNPNDKYEPF
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	137339-65-2
PubChem ID	16131180
InChI Key	OXHYRVSBKWIFES-WWSDOYNLSA-N
Smiles	[H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Thrombin Receptor Agonist Peptide

溶解性	Soluble to 0.90 mg/ml in water

产品说明书 for Thrombin Receptor Agonist Peptide

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Thrombin Receptor Agonist Peptide

参考文献是支持产品生物活性的出版物。

Huang et al (1991) 'Thrombin' receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides. J.Biol.Chem. 266 18435 PMID: 1655750

Vassallo et al (1992) Structure-function relationships in the activation of platelet thrombin receptors by receptor-derived peptides. J.Biol.Chem. 267 6081 PMID: 1313429

Vu et al (1991) Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64 1057 PMID: 1672265

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关键词: Thrombin Receptor Agonist Peptide, Thrombin Receptor Agonist Peptide supplier, Causes, platelet, aggregation, secretion, PAR, Receptors, Protease-Activated, thrombin, receptor, agonists, TRAP, 1185, Tocris Bioscience

2 篇 Thrombin Receptor Agonist Peptide 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Thrombin Receptor Agonist Peptide 的部分引用包括：

Tripathi et al (2014) Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci 55 3912 PMID: 24876278

White et al (2015) A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p. J Endocrinol 194 142 PMID: 25429068

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