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Submit ReviewTLQP 21
说明： VGF-derived peptide
纯度： ≥95% (HPLC)
生物活性 for TLQP 21
TLQP 21 is a VGF-derived peptide; spans residues 556-576 of the precursor sequence. Protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. Increases energy expenditure and prevents early phase diet-induced diabetes.
技术数据 for TLQP 21
| 分子量 | 2432.77 |
| 公式 | C107H170N40O26 |
| 序列 | TLQPPASSRRRHFHHALPPAR |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 869988-94-3 |
| PubChem ID | 16158480 |
| InChI Key | PWWMOXVVMRPYJS-IWCKOKPFSA-N |
| Smiles | [H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for TLQP 21
| 溶解性 | Soluble to 1 mg/ml in water |
产品说明书 for TLQP 21
参考文献 for TLQP 21
参考文献是支持产品生物活性的出版物。
Severini et al (2008) TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cell death induced by serum and potassium deprivation. J.Neurochem. 104 534 PMID: 18173805
Bartolomucci et al (2006) TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity. Proc.Natl.Acad.Sci. USA 103 14584
Jethwa et al (2007) VGF-derived peptide, TLQP-21, regulates food intake and body weight in Siberian hamsters. Endocrinol. 148 4044
If you know of a relevant reference for TLQP 21, please let us know.
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关键词: TLQP 21, TLQP 21 supplier, VGF-derived, peptide, Neurotrophin, Receptors, TLQP21, Other, Apoptosis, Trk, 3051, Tocris Bioscience
1 篇 TLQP 21 的引用文献
引用文献是使用了 Tocris 产品的出版物。 TLQP 21 的部分引用包括：
Hannedouche et al (2013) Identification of the C3a receptor (C3AR1) as the target of the VGF-derived peptide TLQP-21 in rodent cells. Front Pharmacol 288 27434 PMID: 23940034
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