Tobramycin

Pricing Availability   Qty
50 mg / $62In Stock
大包装订单
说明: Aminoglycoside antibiotic
化学名: O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1-4)]-2-deoxy-D-streptamine
说明书
引用文献
评论 (1)

生物活性 for Tobramycin

Tobramycin is an aminoglycoside antibiotic. Exhibits antibacterial activity against strains of Enterobacteriaceae, Pseudomonas and Staphylococcus aureus. Shown to protect lung epithelial cells in vitro against injury from cystic fibrosis bronchial secretions and H2O2.

技术数据 for Tobramycin

分子量 467.52
公式 C18H37N5O9
储存 Store at +4°C
CAS Number 32986-56-4
PubChem ID 36294
InChI Key NLVFBUXFDBBNBW-PBSUHMDJSA-N
Smiles O[C@H]1C[C@@H](N)[C@](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)([H])O[C@@H]1CN

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Tobramycin

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 46.75 100

制备储备液 for Tobramycin

以下数据基于产品分子量 467.52。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.14 mL 10.69 mL 21.39 mL
5 mM 0.43 mL 2.14 mL 4.28 mL
10 mM 0.21 mL 1.07 mL 2.14 mL
50 mM 0.04 mL 0.21 mL 0.43 mL

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参考文献 for Tobramycin

参考文献是支持产品生物活性的出版物。

Dienstag and Neu (1972) In vitro studies of tobramycin, an aminoglycoside antibiotic. Antimicrob.Agents Chemother. 1 41 PMID: 4670427

Cantin and Woods (1993) Protection by antibiotics against myeloperoxidase-dependent cytotoxicity to lung epithelial cells in vitro. PMID: 8380814


If you know of a relevant reference for Tobramycin, please let us know.

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关键词: Tobramycin, Tobramycin supplier, aminoglycoside, antibiotics, antibacterial, Antibiotics, 5390, Tocris Bioscience

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Mechanism of action of tobramycin studied against gentamicin and neomycin m/a.
By Anonymous on 11/30/2019
种属: Human

Mechanism of action of tobramycin was studied along with other aminoglycoside antibiotics such as neomycin and gentamicin.Clinical isolate of P. aeruginosa, PAO1 (PAO1-RH) used to do susceptibility tests.

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