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Submit ReviewTobramycin
说明： Aminoglycoside antibiotic
化学名： O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1-6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1-4)]-2-deoxy-D-streptamine
生物活性 for Tobramycin
Tobramycin is an aminoglycoside antibiotic. Exhibits antibacterial activity against strains of Enterobacteriaceae, Pseudomonas and Staphylococcus aureus. Shown to protect lung epithelial cells in vitro against injury from cystic fibrosis bronchial secretions and H2O2.
技术数据 for Tobramycin
| 分子量 | 467.52 |
| 公式 | C18H37N5O9 |
| 储存 | Store at +4°C |
| CAS Number | 32986-56-4 |
| PubChem ID | 36294 |
| InChI Key | NLVFBUXFDBBNBW-PBSUHMDJSA-N |
| Smiles | O[C@H]1C[C@@H](N)[C@](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)([H])O[C@@H]1CN |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Tobramycin
参考文献 for Tobramycin
参考文献是支持产品生物活性的出版物。
Dienstag and Neu (1972) In vitro studies of tobramycin, an aminoglycoside antibiotic. Antimicrob.Agents Chemother. 1 41 PMID: 4670427
Cantin and Woods (1993) Protection by antibiotics against myeloperoxidase-dependent cytotoxicity to lung epithelial cells in vitro. PMID: 8380814
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关键词: Tobramycin, Tobramycin supplier, aminoglycoside, antibiotics, antibacterial, Antibiotics, 5390, Tocris Bioscience
Tobramycin 的评论
平均评分: 5 (Based on 1 Review.)
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Mechanism of action of tobramycin studied against gentamicin and neomycin m/a.
By
Anonymous on 11/30/2019
种属： Human
Mechanism of action of tobramycin was studied along with other aminoglycoside antibiotics such as neomycin and gentamicin.Clinical isolate of P. aeruginosa, PAO1 (PAO1-RH) used to do susceptibility tests.
