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Submit ReviewTocriscreen 2.0 Micro is a a library of 1280 biologically active compounds from the Tocris catalog. The compounds within this bioactive compound library cover a wide range of pharmacological targets and research areas. Compounds are supplied pre-dissolved in 15 μL 10 mM DMSO solutions. A larger volume is available as Tocriscreen 2.0 Mini (Cat. No. 7151).
This library replaces the Tocriscreen Plus Micro (Cat. No. 6455).
For more information on the Tocriscreen 2.0 Compound Libraries, please download our informative flyer.
If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.
Note: Due to the small volume of this product, please ensure the liquid has settled to the bottom of the well before removing the foil seal.
The Tocriscreen 2.0 Compound Library contains bioactive compounds covering a diverse range of molecular targets; 7-TM receptors (GPCRs; 27%), non-kinase enzymes (21%), kinases including enzyme-linked receptors (20%), ion channels (13%), cell biology targets (9%), nuclear receptors (6%), and transporters and other pharmacological targets (5%).
如需索取 Tocriscreen 2.0 Micro 中包含的化合物列表,请点击下方的索取图块。化合物列表以 Excel 或 SD 格式提供。
储存 | Store at -20°C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Li et al (2011) Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research. 21 196 PMID: 20956998
Beacham et al (2010) Cell-based potassium ion channel screening using the FluxORTM assay. J.Biomol.Screen. 15 44 PMID: 20208034
Hattori et al (2010) Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA. 107 3546 PMID: 20142487
Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell. 17 195 PMID: 26253201
Yu et al (2015) Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell 16 142 PMID: 25658371
If you know of a relevant reference for Tocriscreen 2.0 Micro, please let us know.
关键词: Tocriscreen 2.0 Micro, Tocriscreen 2.0 Micro supplier, biologically, active, pre-dissolved, DMSO, 15ul,, 10mM, solutions, Tocriscreen, Compound, Collections, Screening, Library, Libraries, HTS, HCS, high, throughput, content, 7152, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Tocriscreen 2.0 Micro 的部分引用包括:
Forfar et al (2022) Identification of a novel specific small-molecule melanocortin-2-receptor antagonist. Endocr Connect 11 e220338 PMID: 36515667
Gull et al (2022) Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery. Cold Spring Harb.Protoc. PMID: 36180216
Abduljalil et al (2022) Screening the TocriscreenTM bioactive compound library in search for inhibitors of Candida biofilm formation. APMIS 130 568 PMID: 3579108
Lee & Jeong et al (2022) NMDA Receptor Antagonists Degrade Lipofuscin via Autophagy in Human Retinal Pigment Epithelial Cells Medicina (Kaunas) 58 1129 PMID: 36013596
Fallon et al (2024) Development of a high-throughput screening platform to identify new therapeutic agents for Medulloblastoma Group 3. SLAS Discov. 29 100147 PMID: 38355016
Cetin et al (2024) A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer. Cell Chem.Biol. PMID: 39043186
Pals et al (2023) A quenched size-expanded nucleotide reports activity of the leukemia biomarker Terminal deoxynucleotidyl Transferase (TdT). Angew.Chem.Int.Ed.Engl. 62 e202302796 PMID: 36880583
Parijat et al (2023) Discovery of novel cardiac troponin activators using fluorescence polarization-based high throughput screening assays. Sci.Rep. 13 5216 PMID: 36997544
Benmerah et al (2023) Repurposing small molecules for nephronophthisis and related renal ciliopathies. Kidney Int. 104 245 PMID: 37244473
Kim et al (2023) Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation. Cell Stem Cell 30 973 PMID: 37339636
Liu et al (2020) Ultrasensitive small molecule fluorogenic probe for human heparanase. Chem Sci 12 239 PMID: 34163592
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