Tocriscreen Epigenetics 3.0

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说明: A library of 160 epigenetic compounds (100 μL, 10 mM DMSO solutions) for high throughput screening, high content screening, target validation and assay development
说明书
引用文献 (2)
评论
文献 (1)

生物活性 for Tocriscreen Epigenetics 3.0

Tocriscreen Epigenetics Library is a library of 160 epigenetic compounds (100 μL, 10 mM solutions). Contains compounds covering >40 epigenetic targets including epigenetic readers, writers, erasers and transcriptional modulators. Includes the latest chemical tools to target p300/CBP, PCAF, BRPF1 and SMYD2.

This library replaces the Tocriscreen Epigenetics Library (Cat. No. 6801).

If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.

Key Format and Product Details for Tocriscreen Epigenetics 3.0

  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Pre-dissolved in DMSO
  • Exceptional purity
  • Many compounds are exclusive to Tocris
  • Full chemical and biological data available
  • Proven solubility, biological activity and stability in DMSO
Target Classes Covered by the Tocriscreen Epigenetics Library

The Tocriscreen Epigenetics Compound Library contains bioactive compounds covering a diverse range of molecular targets within the following categories: epigenetic writers (43%), transcription modulators (23%), epigenetic erasers (19%), and epigenetic readers (16%).

索取化合物列表

如需索取 Tocriscreen Epigenetics 3.0 中包含的化合物列表,请点击下方的索取图块。化合物列表以 Excel 或 SD 格式提供。

索取化合物列表: Tocriscreen Epigenetics 3.0

技术数据 for Tocriscreen Epigenetics 3.0

储存 Store at -20°C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Tocriscreen Epigenetics 3.0

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参考文献 for Tocriscreen Epigenetics 3.0

参考文献是支持产品生物活性的出版物。

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关键词: Tocriscreen Epigenetics 3.0, Tocriscreen Epigenetics 3.0 supplier, Tocriscreens, Epigenetics, Library, compounds, libraries, screening, tools, histones, readers, writers, erasers, bromodomains, BET, BRD, DNA, methyltransferases, HMTs, MBT, L3MBT, RNA, polymerases, demethylases, HDMs, acetyltransferases, HATs, deacetylases, HDACS, KDMs, modulators, t, Tocriscreen, Compound, Libraries, 7578, Tocris Bioscience

2 篇 Tocriscreen Epigenetics 3.0 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Tocriscreen Epigenetics 3.0 的部分引用包括:

Andricovich et al (2018) Loss of KDM6A activates super-enhancers to induce gender-specific squamous-like pancreatic cancer and confers sensitivity to BET inhibitors. Cancer Cell 33 512 PMID: 29533787

Zhang et al (2023) Deciphering a global source of non-genetic heterogeneity in cancer cells. Nucleic Acids Res. 51 9019 PMID: 37587722


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Tocriscreen Compound Libraries

Tocriscreen Compound Libraries

This brochure gives an overview of the unique TocriscreenTM bioactive compound library range, including

  • Tocriscreen 2.0 Compound Library
  • Focused Tocriscreen Libraries
  • Tocriscreen FDA-approved Drug Library
  • Tocriscreen PRO Custom Service