TRAP-6

Cat. No. 3497 8 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： PAR₁ peptide fragment (residues 42-47); acts as a PAR₁ agonist

别名： Thrombin receptor activator peptide 6

纯度： ≥95% (HPLC)

引用文献 (8)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for TRAP-6

TRAP-6 is a peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR₁) that acts as a PAR₁ agonist. Stimulates platelet aggregation (EC₅₀ = 0.8 μM), promotes intracellular Ca²⁺ mobilization and induces rapid phosphodiesterase 3A (PDE3A) phosphorylation in vitro.

技术数据 for TRAP-6

分子量	748.88
公式	C₃₄H₅₆N₁₀O₉
序列	SFLLRN
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	141136-83-6
PubChem ID	9831933
InChI Key	HAGOWCONESKMDW-FRSCJGFNSA-N
Smiles	[H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for TRAP-6

溶解性	Soluble to 1 mg/ml in water

产品说明书 for TRAP-6

分析证书/产品说明书

化学品安全技术说明书

参考文献 for TRAP-6

参考文献是支持产品生物活性的出版物。

Vassallo et al (1992) Structure-function relationships in the activation of platelet thrombin receptors by receptor derived peptides. J.Biol.Chem. 267 6081 PMID: 1313429

Kaufmann et al (1999) PAR 1-type thrombin receptors are involved in thrombin-induced calcium signaling in human meningioma cells. J.Neurooncol. 42 131 PMID: 10421070

Hunter et al (2009) Protein kinase C-mediated phosphorylation and activation of PDE3A regulates cAMP levels in human platelets. J.Biol.Chem. 284 12339 PMID: 19261611

If you know of a relevant reference for TRAP-6, please let us know.

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关键词: TRAP-6, TRAP-6 supplier, PAR1, peptide, fragment, residues, 42-47, agonists, Receptors, Protease-Activated, proteinase-activated, Thrombin, receptor, activator, peptide6, 6, 3497, Tocris Bioscience