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Submit ReviewTravaprost
说明： Potent and selective FP prostaglandin receptor agonist
化学名： (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methyethyl ester
纯度： ≥98% (HPLC)
生物活性 for Travaprost
Travaprost is a FP prostaglandin receptor agonist. Exhibits submicromolar affinity for DP, EP, IP and TP receptors. Stimulates intracellular Ca2+ mobilization. Ocular hypotensive agent.
技术数据 for Travaprost
| 分子量 | 500.55 |
| 公式 | C26H35F3O6 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 157283-68-6 |
| PubChem ID | 5282226 |
| InChI Key | MKPLKVHSHYCHOC-AHTXBMBWSA-N |
| Smiles | O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2)[C@H](O)C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Travaprost
参考文献 for Travaprost
参考文献是支持产品生物活性的出版物。
Hellberg et al (2001) Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J.Ocul.Pharmacol.Ther. 17 421 PMID: 11765147
Sharif et al (1999) [3H]AL-5848 ([3H]9beta-(+)-Fluprostenol). Carboxylic acid of travo. (AL-6221), a novel FP prostaglandin to study the pharmacology and autoradiographic localization of the FP receptor. J.Pharm.Pharmacol. 51 685 PMID: 10454045
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关键词: Travaprost, Travaprost supplier, Supplier, Travoprost, FP, receptor, agonist, prostaglandin, F2a, F2alpha, ocular, hypotensive, Prostanoid, Receptors, 4218, Tocris Bioscience
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