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Tris DBA

Cat. No. 3416 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3416 has been discontinued.

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说明： N-myristoyltransferase-1 inhibitor; antiproliferative
化学名： Tris(dibenzylideneacetone) dipalladium
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for Tris DBA

Tris DBA is a N-myristoyltransferase-1 (NMT-1) inhibitor that prevents activation of MAPK, PI 3-K and STAT3 signaling pathways. Exhibits antiproliferative activity against melanoma cells in vitro and in vivo. Also used as a cyclization catalyst.

技术数据 for Tris DBA

分子量 915.73
公式 C51H42O3Pd2
储存 Store at RT
CAS Number 51364-51-3
PubChem ID 9811564
InChI Key CYPYTURSJDMMMP-WVCUSYJESA-N
Smiles [Pd].[Pd].O=C(\C=C\C1=CC=CC=C1)/C=C/C1=CC=CC=C1.O=C(\C=C\C1=CC=CC=C1)/C=C/C1=CC=CC=C1.O=C(\C=C\C1=CC=CC=C1)/C=C/C1=CC=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Tris DBA

参考文献是支持产品生物活性的出版物。

Bhandarkar et al (2008) Tris(Dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo. Clin.Cancer Res. 14 5743 PMID: 18794083

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关键词: Tris DBA, Tris DBA supplier, N-myristoyltransferase-1, inhibitors, inhibits, antiproliferative, Transferases, TrisDBA, Other, Post-translational, Modifications, 3416, Tocris Bioscience

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